{"id":264,"title":"Uncoupling of oxidative phosphorylation leading to growth inhibition via ATP depletion associated cell death","short_name":"Uncoupling of OXPHOS leading to growth inhibition via ATP depletion associated cell death","created_at":"2018-05-24T14:16:25.000-04:00","updated_at":"2024-06-20T02:54:56.000-04:00","corresponding_author":{"id":322,"created_at":"2016-06-30T07:13:47.000-04:00","updated_at":"2026-09-02T05:43:30.000-04:00","subscribed":true,"novice":true},"aop_stressors":[],"aop_mies":[{"event_id":1446,"event":"Decrease, Coupling of oxidative phosphorylation","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":1771,"event":"Decrease, Adenosine triphosphate pool","event_type":"KeyEvent"},{"event_id":55,"event":"Increase, Cell injury/death","event_type":"KeyEvent"}],"aop_aos":[{"event_id":1521,"event":"Decrease, Growth","event_type":"AdverseOutcome"}],"relationships":[{"relation":2377,"upstream_event_id":1446,"upstream_event":"Decrease, Coupling of oxidative phosphorylation","downstream_event_id":1771,"downstream_event":"Decrease, Adenosine triphosphate pool"},{"relation":3235,"upstream_event_id":1771,"upstream_event":"Decrease, Adenosine triphosphate pool","downstream_event_id":55,"downstream_event":"Increase, Cell injury/death"},{"relation":3236,"upstream_event_id":55,"upstream_event":"Increase, Cell injury/death","downstream_event_id":1521,"downstream_event":"Decrease, Growth"}]}