AOP-Wiki

API

All Key Events

Showing 1 to 25 of 1911 Key Events

ID	Title	Event Component Count	Biological Organization	Created At	Last Updated	AOPs

342	Increased, Lethality Short Name Increased, Lethality	0		Nov 29, 2016	Nov 29, 2016	None
29	Reduction in, Angiogenic sprouts Short Name Reduction in, Angiogenic sprouts	0		Nov 29, 2016	Nov 29, 2016	None
59	Inhibition of Apoptosis in Altered Hepatic Foci, Changes in Cellular Growth Homeostasis Short Name	0		Nov 29, 2016	Nov 29, 2016	None
60	Induction, Chitin degradation and resorption Short Name	0		Nov 29, 2016	Nov 29, 2016	None
139	N/A, Hepatotoxicity, Hepatopathy, including a constellation of observable effects Short Name	1	Tissue	Nov 29, 2016	Nov 29, 2016	41: Sustained AhR Activation leading to Rodent Liver Tumours
183	Abnormal, Morphogenesis Short Name Abnormal, Morphogenesis	0		Nov 29, 2016	Nov 29, 2016	None
222	Elimination of (high doses), Posterior cardinal vein Short Name	0		Nov 29, 2016	Nov 29, 2016	None
238	Induction, Pre-mature molting Short Name Induction, Pre-mature molting	0		Nov 29, 2016	Nov 29, 2016	None
301	Binding, VEGF-A Short Name Binding, VEGF-A	0		Nov 29, 2016	Nov 29, 2016	None
302	Production, VEGF-A Short Name Production, VEGF-A	0		Nov 29, 2016	Nov 29, 2016	None
304	Decreased, VegfR2 Short Name Decreased, VegfR2	0		Nov 29, 2016	Nov 29, 2016	None
312	N/A, Allergic contact dermatitis on challenge Short Name	0	Individual	Nov 29, 2016	Nov 29, 2016	None
315	Decreased, Body length Short Name Decreased, Body length	0		Nov 29, 2016	Nov 29, 2016	None
320	Increase, Curved body axis Short Name Increase, Curved body axis	0		Nov 29, 2016	Nov 29, 2016	None
336	Increase, Heritable mutations in offspring Short Name	1	Individual	Nov 29, 2016	Nov 29, 2016	15: Alkylation of DNA in male pre-meiotic germ cells leading to heritable mutations
366	Increased, Structural malformations Short Name Increased, Structural malformations	0		Nov 29, 2016	Nov 29, 2016	None
377	Increased, Proliferation/Clonal Expansion of Mutant Cells (Pre-Neoplastic Lesions/Altered Hepatic Foci (AHF)) Short Name	0		Nov 29, 2016	Nov 29, 2016	None
378	Tumorigenesis, Hepatocellular carcinoma Short Name Tumorigenesis, Hepatocellular carcinoma	1	Individual	Nov 29, 2016	Nov 29, 2016	46: AFB1: Mutagenic Mode-of-Action leading to Hepatocellular Carcinoma (HCC)
380	Activation, Pre-MIE: Metabolism of AFB1 Short Name Activation, Pre-MIE: Metabolism of AFB1	0	Molecular	Nov 29, 2016	Nov 29, 2016	None
384	Increased, Clonal Expansion / Cell Proliferatin to form Pre-Neoplastic Altered Hepatic Foci Short Name	0		Nov 29, 2016	Nov 29, 2016	None
387	Binding of agonist, NMDARs Short Name Binding of agonist, NMDARs	0	Molecular	Nov 29, 2016	Nov 29, 2016	None
397	Response, Keratinocytes Short Name Response, Keratinocytes	0	Cellular	Nov 29, 2016	Nov 29, 2016	None
423	Increased, Clonal Expansion / Cell Proliferation to Form Pre-Neoplastic Altered Hepatic Foci Short Name	0		Nov 29, 2016	Nov 29, 2016	None
427	Down Regulation, K-Cl co-transporter 2 (KCC2) Short Name	0	Cellular	Nov 29, 2016	Nov 29, 2016	None
428	Delay, Developmental GABA shift Short Name Delay, Developmental GABA shift	0	Cellular	Nov 29, 2016	Nov 29, 2016	None