Key Event Relationships (KERs)

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Showing 101 to 125 of 3130 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
173 167: Activation, LXR 54: Up Regulation, CD36 Nov 29, 2016 Dec 3, 2016
174 167: Activation, LXR 66: Activation, ChREBP Nov 29, 2016 Dec 3, 2016
175 167: Activation, LXR 116: Activation, FAS Nov 29, 2016 Dec 3, 2016
176 167: Activation, LXR 258: Activation, SCD-1 Nov 29, 2016 Dec 3, 2016
177 167: Activation, LXR 264: Activation, SREBP-1c Nov 29, 2016 Dec 3, 2016
182 173: N/A, Methemoglobinemia, decreased hemoglobin, hematocrit, red blood cell number 321: N/A, Cyanosis occurs Nov 29, 2016 Dec 3, 2016
215 195: Inhibition, NMDARs 191: Neuronal dysfunction Nov 29, 2016 Dec 3, 2016 None
188 178: Mitochondrial electron transport chain, disrupted 40: Mitochondrial ATP production, decreased Nov 29, 2016 Dec 3, 2016
190 179: Decrease, Fatty acid β-oxidation 327: Accumulation, Fatty acid Nov 29, 2016 Dec 3, 2016
196 183: Abnormal, Morphogenesis 342: Increased, Lethality Nov 29, 2016 Dec 3, 2016 None
198 350: Increase, Mortality 328: Decrease, Fecundity Nov 29, 2016 Dec 3, 2016 None
199 350: Increase, Mortality 361: Decline, Population Nov 29, 2016 Dec 3, 2016 None
228 201: Binding of antagonist, NMDA receptors 341: Impairment, Learning and memory Nov 29, 2016 Dec 3, 2016 None
200 351: Increased Mortality 361: Decline, Population Nov 29, 2016 Dec 3, 2016 None
212 193: Decreased, Nitric Oxide 166: Decreased, Long-term potentiation (LTP) Nov 29, 2016 Dec 3, 2016
214 195: Inhibition, NMDARs 341: Impairment, Learning and memory Nov 29, 2016 Dec 3, 2016 None
136 119: N/A, Gap 49: Reduction, Ca and HCO3 transport to shell gland Nov 29, 2016 Dec 3, 2016
123 106: Reduction, Eggshell thickness 253: N/A, Reproductive failure Nov 29, 2016 Dec 3, 2016
126 111: Agonism, Estrogen receptor 363: Altered, Reproductive behaviour Nov 29, 2016 Dec 3, 2016
127 111: Agonism, Estrogen receptor 364: Impaired development of, Reproductive organs Nov 29, 2016 Dec 3, 2016
133 116: Activation, FAS 89: Synthesis, De Novo Fatty Acid (FA) Nov 29, 2016 Dec 3, 2016
135 328: Decrease, Fecundity 361: Decline, Population Nov 29, 2016 Dec 3, 2016 None
146 134: Increase, Kupffer cell activation 209: Peptide Oxidation Nov 29, 2016 Dec 3, 2016 None
154 140: Decreased, HSD17B10 expression 8: Decreased, 3-hydroxyacyl-CoA dehydrogenase type-2 activity Nov 29, 2016 Dec 3, 2016
158 142: Hyperplasia, Hyperplasia 334: Promotion, Hepatocelluar carcinoma Nov 29, 2016 Dec 3, 2016