Prototypical Stressors

Showing 201 to 225 of 855 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

202	Fluoxetine		3 AOPs 195: 5-hydroxytryptamine transporter (5-HTT) inhibition leading to population increase 97: 5-hydroxytryptamine transporter (5-HTT; SERT) inhibition leading to population decline 203: 5-hydroxytryptamine transporter inhibition leading to decreased reproductive success and population decline
203	Fluvoxamine	Fluvoxamine, CAS-RN: 54739-18-3, DTXSID2044002	2 AOPs 195: 5-hydroxytryptamine transporter (5-HTT) inhibition leading to population increase 203: 5-hydroxytryptamine transporter inhibition leading to decreased reproductive success and population decline
204	Tetrahydrocannabinol	1-trans-delta-9-Tetrahydrocannabinol, CAS-RN: 1972-08-3, DTXSID6021327	None
205	pirinixic acid	Pirinixic acid, CAS-RN: 50892-23-4, DTXSID4020290	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
206	Nafenopin	Nafenopin, CAS-RN: 3771-19-5, DTXSID8020911	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
207	ciprofibrate	Ciprofibrate, CAS-RN: 52214-84-3, DTXSID8020331	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
208	Gemfibrozil	Gemfibrozil, CAS-RN: 25812-30-0, DTXSID0020652	2 AOPs 37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents 323: PPARalpha Agonism Leading to Decreased Viable Offspring via Decreased 11-Ketotestosterone
209	trichloroacetic acid	Trichloroacetic acid, CAS-RN: 76-03-9, DTXSID1021378	None
210	Bezafibrate	Bezafibrate, CAS-RN: 41859-67-0, DTXSID3029869	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
211	Fenofibrate	Fenofibrate, CAS-RN: 49562-28-9, DTXSID2029874	2 AOPs 37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents 323: PPARalpha Agonism Leading to Decreased Viable Offspring via Decreased 11-Ketotestosterone
212	iopanoic acid	Iopanoic acid, CAS-RN: 96-83-3, DTXSID6023159	155: Deiodinase 2 inhibition leading to increased mortality via reduced posterior swim bladder inflation
213	fenoxycarb	Fenoxycarb, CAS-RN: 72490-01-8, DTXSID7032393	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
214	DIOFENOLAN	Diofenolan, CAS-RN: 63837-33-2, DTXSID2041884	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
215	pyriproxyfen	Pyriproxyfen, CAS-RN: 95737-68-1, DTXSID1032640	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
216	(7S)-Hydroprene	(7S)-Hydroprene, CAS-RN: 65733-18-8, DTXSID6035784	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
217	kinoprene	Kinoprene, CAS-RN: 42588-37-4, DTXSID3032624	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
218	metofluthrin	Metofluthrin, CAS-RN: 240494-70-6, DTXSID4034738	107: Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat
219	Econazole		None
220	5-(N,N-hexamethylene) amiloride (HMA)		None
221	Small molecules: ITB3, ITB4, ITB5, ITB9		None
222	MPP+		3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits
223	Etoposide	Etoposide, CAS-RN: 33419-42-0, DTXSID5023035	202: Inhibitor binding to topoisomerase II leading to infant leukaemia
224	nanoparticles		3 AOPs 144: Endocytic lysosomal uptake leading to liver fibrosis 392: Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation 451: Interaction with lung resident cell membrane components leads to lung cancer
225	ROS		144: Endocytic lysosomal uptake leading to liver fibrosis
226	o-methyl-serine dodecylamide hydrochloride (MSDH)		144: Endocytic lysosomal uptake leading to liver fibrosis