| August 28, 2023 08:41 |
Nathalie Delrue |
Oecd Status changed from EAGMST Under Review to WPHA/WNT Endorsed. |
| May 24, 2023 20:18 |
Takao Ashikaga |
Relationship:2928 was added to AOP. |
| May 24, 2023 20:17 |
Takao Ashikaga |
Relationship:2927 was removed from AOP. |
| May 24, 2023 04:50 |
Takao Ashikaga |
Relationship:2927 was added to AOP. |
| May 24, 2023 04:42 |
Takao Ashikaga |
Event:984 was added to AOP. |
| May 24, 2023 04:41 |
Takao Ashikaga |
Event:986 was removed from AOP. |
| May 24, 2023 04:40 |
Takao Ashikaga |
Relationship:2004 was removed from AOP. |
| May 24, 2023 00:42 |
Takao Ashikaga |
Event:984 was removed from AOP. |
| May 24, 2023 00:42 |
Takao Ashikaga |
Event:984 was added to AOP. |
| March 02, 2023 03:35 |
Takao Ashikaga |
Weight of Evidence Summary and References updated. |
| March 02, 2023 00:48 |
Takao Ashikaga |
Domain of Applicability updated. |
| March 02, 2023 00:33 |
Takao Ashikaga |
Abstract, Weight of Evidence Summary, and References updated. |
| March 01, 2023 22:55 |
Takao Ashikaga |
Short name updated. |
| October 14, 2022 00:39 |
Kiyoshi Kushima |
Event:983 was removed from AOP. |
| October 14, 2022 00:36 |
Kiyoshi Kushima |
Event:983 was added to AOP. |
| October 13, 2022 23:51 |
Kiyoshi Kushima |
Title updated. |
| October 11, 2022 03:19 |
Takao Ashikaga |
References updated. |
| October 11, 2022 03:17 |
Takao Ashikaga |
Weight of Evidence Summary and Considerations for Potential Applications of the AOP updated. |
| October 11, 2022 03:07 |
Takao Ashikaga |
Essentiality of the Key Events updated. |
| October 11, 2022 03:05 |
Takao Ashikaga |
Domain of Applicability and Weight of Evidence Summary updated. |
| October 11, 2022 02:58 |
Takao Ashikaga |
Abstract and Background updated. |
| October 10, 2022 22:49 |
Takao Ashikaga |
Abstract and Authors updated. |
| May 23, 2021 01:14 |
Yutaka Kimura |
Abstract, Domain of Applicability, Essentiality of the Key Events, Weight of Evidence Summary, Considerations for Potential Applications of the AOP, and References updated. |
| May 03, 2021 05:56 |
Yutaka Kimura |
Essentiality of the Key Events updated. |
| May 03, 2021 02:32 |
Yutaka Kimura |
Essentiality of the Key Events and Weight of Evidence Summary updated. |
| May 03, 2021 02:25 |
Yutaka Kimura |
Essentiality of the Key Events and References updated. |
| May 03, 2021 01:03 |
Yutaka Kimura |
Essentiality of the Key Events, Weight of Evidence Summary, Quantitative Considerations, Considerations for Potential Applications of the AOP, and References updated. |
| May 01, 2021 01:35 |
Yutaka Kimura |
Essentiality of the Key Events and Weight of Evidence Summary updated. |
| May 01, 2021 00:27 |
Yutaka Kimura |
Stressor:636 was added to AOP. |
| May 01, 2021 00:26 |
Yutaka Kimura |
Stressor:617 was added to AOP. |
| May 01, 2021 00:25 |
Yutaka Kimura |
Stressor:616 - Evidence changed from null to High. |
| May 01, 2021 00:25 |
Yutaka Kimura |
Stressor:616 was added to AOP. |
| May 01, 2021 00:25 |
Yutaka Kimura |
Stressor:638 was added to AOP. |
| May 01, 2021 00:24 |
Yutaka Kimura |
Stressor:614 was added to AOP. |
| May 01, 2021 00:23 |
Yutaka Kimura |
Stressor:612 was added to AOP. |
| May 01, 2021 00:22 |
Yutaka Kimura |
Stressor:637 was added to AOP. |
| May 01, 2021 00:22 |
Yutaka Kimura |
Stressor:637 was removed from AOP. |
| May 01, 2021 00:21 |
Yutaka Kimura |
Stressor:637 - Evidence changed from null to High. |
| May 01, 2021 00:21 |
Yutaka Kimura |
Stressor:612 was removed from AOP. |
| May 01, 2021 00:19 |
Yutaka Kimura |
Stressor:637 was added to AOP. |
| April 30, 2021 23:31 |
Yutaka Kimura |
Stressor:612 - Evidence changed from null to High. |
| April 30, 2021 23:31 |
Yutaka Kimura |
Stressor:612 was added to AOP. |
| April 30, 2021 21:07 |
Yutaka Kimura |
Essentiality of the Key Events, Weight of Evidence Summary, and Background updated. |
| April 29, 2021 04:08 |
Yutaka Kimura |
Weight of Evidence Summary updated. |
| April 28, 2021 20:25 |
Yutaka Kimura |
Relationship:2004 - Quantitative understanding changed from Not Specified to High. |
| April 28, 2021 19:59 |
Yutaka Kimura |
Background updated. |
| April 28, 2021 04:02 |
Yutaka Kimura |
Weight of Evidence Summary and References updated. |
| April 28, 2021 03:20 |
Yutaka Kimura |
References updated. |
| April 28, 2021 02:44 |
Yutaka Kimura |
Domain of Applicability, Essentiality of the Key Events, References, and Background updated. |
| December 21, 2020 21:47 |
Yutaka Kimura |
Abstract and Background updated. |
| December 21, 2020 20:30 |
Yutaka Kimura |
Title updated. |
| December 21, 2020 20:28 |
Yutaka Kimura |
References updated. |
| December 21, 2020 19:58 |
Yutaka Kimura |
Stressor:488 was added to AOP. |
| December 21, 2020 19:58 |
Yutaka Kimura |
Stressor:608 was removed from AOP. |
| December 21, 2020 19:57 |
Yutaka Kimura |
Stressor:611 was added to AOP. |
| December 21, 2020 19:54 |
Yutaka Kimura |
Stressor:610 was removed from AOP. |
| December 21, 2020 19:52 |
Yutaka Kimura |
Stressor:610 was added to AOP. |
| December 21, 2020 19:50 |
Yutaka Kimura |
Stressor:609 - Evidence changed from null to High. |
| December 21, 2020 19:49 |
Yutaka Kimura |
Stressor:609 was added to AOP. |
| December 21, 2020 19:49 |
Yutaka Kimura |
Stressor:608 was added to AOP. |
| December 21, 2020 19:48 |
Yutaka Kimura |
Stressor:486 - Evidence changed from null to High. |
| December 21, 2020 19:48 |
Yutaka Kimura |
Stressor:486 was added to AOP. |
| December 21, 2020 19:47 |
Yutaka Kimura |
Stressor:492 - Evidence changed from null to High. |
| December 21, 2020 19:47 |
Yutaka Kimura |
Stressor:492 was added to AOP. |
| December 21, 2020 19:01 |
Yutaka Kimura |
Background updated. |
| December 21, 2020 18:57 |
Yutaka Kimura |
Abstract updated. |
| December 16, 2020 18:25 |
Yutaka Kimura |
Abstract updated. |
| December 16, 2020 18:23 |
Yutaka Kimura |
Abstract updated. |
| March 16, 2020 21:59 |
Yutaka Kimura |
Quantitative Considerations and References updated. |
| March 16, 2020 21:45 |
Yutaka Kimura |
Considerations for Potential Applications of the AOP updated. |
| March 16, 2020 21:43 |
Yutaka Kimura |
Domain of Applicability, Essentiality of the Key Events, and Weight of Evidence Summary updated. |
| March 16, 2020 21:35 |
Yutaka Kimura |
Abstract and Background updated. |
| March 13, 2020 02:28 |
Yutaka Kimura |
Relationship:2002 - Quantitative understanding changed from Not Specified to Moderate. |
| March 09, 2020 03:18 |
Yutaka Kimura |
Relationship:2003 - Quantitative understanding changed from Not Specified to Moderate. |
| March 09, 2020 00:37 |
Yutaka Kimura |
Relationship:2002 - Quantitative understanding changed from Moderate to Not Specified. |
| March 09, 2020 00:34 |
Yutaka Kimura |
Relationship:2002 - Quantitative understanding changed from Not Specified to Moderate. |
| January 07, 2020 10:33 |
Nathalie Delrue |
Oecd Status changed from null to EAGMST Under Review. Saaop Status changed from null to EAGMST Under Review. |
| December 29, 2019 21:39 |
Yutaka Kimura |
Essentiality of the Key Events updated. |
| December 29, 2019 21:31 |
Yutaka Kimura |
Quantitative Considerations updated. |
| December 29, 2019 21:30 |
Yutaka Kimura |
Quantitative Considerations updated. |
| December 29, 2019 21:25 |
Yutaka Kimura |
Weight of Evidence Summary and Quantitative Considerations updated. |
| December 29, 2019 20:54 |
Yutaka Kimura |
Weight of Evidence Summary updated. |
| December 29, 2019 20:48 |
Yutaka Kimura |
Weight of Evidence Summary and Quantitative Considerations updated. |
| December 29, 2019 20:31 |
Yutaka Kimura |
Essentiality of the Key Events updated. |
| December 29, 2019 19:59 |
Yutaka Kimura |
Weight of Evidence Summary updated. |
| December 15, 2019 20:41 |
Yutaka Kimura |
Stressor:518 was added to AOP. |
| December 15, 2019 20:32 |
Yutaka Kimura |
Stressor:517 was removed from AOP. |
| December 15, 2019 20:32 |
Yutaka Kimura |
Stressor:517 was added to AOP. |
| December 15, 2019 20:27 |
Yutaka Kimura |
Quantitative Considerations updated. |
| December 15, 2019 20:05 |
Yutaka Kimura |
Relationship:2004 - Quantitative understanding changed from High to Not Specified. |
| December 15, 2019 20:04 |
Yutaka Kimura |
Relationship:2003 - Quantitative understanding changed from High to Not Specified. |
| December 15, 2019 20:04 |
Yutaka Kimura |
Relationship:2002 - Quantitative understanding changed from High to Not Specified. |
| November 18, 2019 02:38 |
Yutaka Kimura |
Essentiality of the Key Events updated. |
| November 18, 2019 02:34 |
Yutaka Kimura |
Stressor:492 was removed from AOP. |
| November 18, 2019 02:34 |
Yutaka Kimura |
Stressor:488 was removed from AOP. |
| November 18, 2019 02:34 |
Yutaka Kimura |
Stressor:487 was removed from AOP. |
| November 18, 2019 02:33 |
Yutaka Kimura |
Stressor:486 was removed from AOP. |
| November 18, 2019 00:29 |
Yutaka Kimura |
References updated. |
| November 17, 2019 21:39 |
Yutaka Kimura |
Weight of Evidence Summary updated. |
| November 17, 2019 21:34 |
Yutaka Kimura |
Essentiality of the Key Events updated. |
| November 17, 2019 21:29 |
Yutaka Kimura |
Domain of Applicability updated. |
| November 17, 2019 21:23 |
Yutaka Kimura |
Relationship:2004 was added to AOP. |
| November 17, 2019 21:22 |
Yutaka Kimura |
Relationship:2003 was added to AOP. |
| November 17, 2019 21:22 |
Yutaka Kimura |
Relationship:2002 was added to AOP. |
| November 17, 2019 21:20 |
Yutaka Kimura |
Relationship:2000 was removed from AOP. |
| November 17, 2019 21:20 |
Yutaka Kimura |
Relationship:2001 was removed from AOP. |
| November 17, 2019 21:19 |
Yutaka Kimura |
Relationship:2001 was added to AOP. |
| November 17, 2019 21:18 |
Yutaka Kimura |
Relationship:2000 was added to AOP. |
| November 17, 2019 21:11 |
Yutaka Kimura |
Event:986 was added to AOP. |
| November 17, 2019 21:09 |
Yutaka Kimura |
Event:1701 was removed from AOP. |
| November 17, 2019 21:09 |
Yutaka Kimura |
Event:202 was added to AOP. |
| November 17, 2019 21:05 |
Yutaka Kimura |
Event:1702 was added to AOP. |
| November 17, 2019 21:05 |
Yutaka Kimura |
Event:1701 was added to AOP. |
| November 17, 2019 21:04 |
Yutaka Kimura |
Event:1700 was added to AOP. |
| November 17, 2019 21:03 |
Yutaka Kimura |
Event:1572 was removed from AOP. |
| November 17, 2019 21:03 |
Yutaka Kimura |
Event:202 was removed from AOP. |
| November 17, 2019 21:03 |
Yutaka Kimura |
Event:1569 was removed from AOP. |
| November 17, 2019 21:03 |
Yutaka Kimura |
Event:986 was removed from AOP. |
| November 17, 2019 21:02 |
Yutaka Kimura |
Relationship:1921 was removed from AOP. |
| November 17, 2019 21:02 |
Yutaka Kimura |
Relationship:1920 was removed from AOP. |
| November 17, 2019 21:02 |
Yutaka Kimura |
Event:1644 was removed from AOP. |
| November 17, 2019 21:02 |
Yutaka Kimura |
Relationship:1923 was removed from AOP. |
| November 17, 2019 21:02 |
Yutaka Kimura |
Relationship:1922 was removed from AOP. |
| November 17, 2019 21:01 |
Yutaka Kimura |
Event:1571 was removed from AOP. |
| November 17, 2019 21:01 |
Yutaka Kimura |
Event:1570 was removed from AOP. |
| November 17, 2019 21:01 |
Yutaka Kimura |
Relationship:1813 was removed from AOP. |
| November 17, 2019 21:00 |
Yutaka Kimura |
Relationship:1814 was removed from AOP. |
| November 17, 2019 20:51 |
Yutaka Kimura |
Background updated. |
| November 17, 2019 20:47 |
Yutaka Kimura |
Title and Abstract updated. |
| August 07, 2019 05:52 |
Yutaka Kimura |
Status changed from Under development: Not open for comment. Do not cite to Open for citation & comment. |
| August 07, 2019 05:40 |
Yutaka Kimura |
Weight of Evidence Summary and Considerations for Potential Applications of the AOP updated. |
| June 25, 2019 20:29 |
Yutaka Kimura |
Stressor:492 - Evidence changed from null to High. |
| June 25, 2019 20:29 |
Yutaka Kimura |
Stressor:492 was added to AOP. |
| June 25, 2019 20:28 |
Yutaka Kimura |
Stressor:485 was removed from AOP. |
| June 25, 2019 19:32 |
Yutaka Kimura |
Relationship:1822 was removed from AOP. |
| June 24, 2019 00:22 |
Yutaka Kimura |
Taxonomic term: Rattus norvegicus was added to AOP. |
| June 24, 2019 00:21 |
Yutaka Kimura |
Taxonomic term: Mus musculus was added to AOP. |
| June 24, 2019 00:20 |
Yutaka Kimura |
Taxonomic term: Homo sapiens was added to AOP. |
| June 23, 2019 23:59 |
Yutaka Kimura |
Sex term: Mixed was added to AOP. |
| June 23, 2019 23:58 |
Yutaka Kimura |
Life stage term: Not Otherwise Specified was added to AOP. |
| June 23, 2019 23:56 |
Yutaka Kimura |
Abstract updated. |
| June 01, 2019 00:38 |
Yutaka Kimura |
Stressor:491 was added to AOP. |
| June 01, 2019 00:38 |
Yutaka Kimura |
Stressor:490 was added to AOP. |
| June 01, 2019 00:37 |
Yutaka Kimura |
Stressor:489 was added to AOP. |
| June 01, 2019 00:37 |
Yutaka Kimura |
Stressor:488 was added to AOP. |
| June 01, 2019 00:36 |
Yutaka Kimura |
Stressor:487 was added to AOP. |
| June 01, 2019 00:32 |
Yutaka Kimura |
Stressor:486 was added to AOP. |
| June 01, 2019 00:32 |
Yutaka Kimura |
Stressor:485 was added to AOP. |
| June 01, 2019 00:06 |
Yutaka Kimura |
Abstract, Domain of Applicability, Essentiality of the Key Events, Weight of Evidence Summary, References, and Background updated. |
| May 23, 2019 03:00 |
Yutaka Kimura |
Relationship:1923 was added to AOP. |
| May 23, 2019 03:00 |
Yutaka Kimura |
Relationship:1922 was added to AOP. |
| May 23, 2019 02:59 |
Yutaka Kimura |
Relationship:1822 was added to AOP. |
| May 23, 2019 02:58 |
Yutaka Kimura |
Relationship:1921 was added to AOP. |
| May 23, 2019 02:57 |
Yutaka Kimura |
Relationship:1871 was removed from AOP. |
| May 23, 2019 02:56 |
Yutaka Kimura |
Event:1644 was added to AOP. |
| May 23, 2019 02:54 |
Yutaka Kimura |
Relationship:1920 was added to AOP. |
| May 23, 2019 02:53 |
Yutaka Kimura |
Event:1573 was removed from AOP. |
| May 23, 2019 02:34 |
Yutaka Kimura |
Relationship:1870 was removed from AOP. |
| May 23, 2019 02:34 |
Yutaka Kimura |
Relationship:1825 was removed from AOP. |
| March 27, 2019 18:32 |
Yutaka Kimura |
Event:1569 was added to AOP. |
| March 22, 2019 03:22 |
Yutaka Kimura |
Essentiality of the Key Events, References, and Background updated. |
| March 14, 2019 02:57 |
Yutaka Kimura |
References updated. |
| March 12, 2019 20:41 |
Yutaka Kimura |
Relationship:1871 - Evidence changed from null to High. Quantitative understanding changed from null to High. |
| March 12, 2019 20:41 |
Yutaka Kimura |
Relationship:1870 - Evidence changed from null to High. Quantitative understanding changed from null to High. |
| March 12, 2019 20:39 |
Yutaka Kimura |
Relationship:1826 was removed from AOP. |
| March 12, 2019 20:39 |
Yutaka Kimura |
Relationship:1871 was added to AOP. |
| March 12, 2019 20:38 |
Yutaka Kimura |
Relationship:1870 was added to AOP. |
| March 12, 2019 20:36 |
Yutaka Kimura |
Event:202 was added to AOP. |
| February 05, 2019 20:30 |
Yutaka Kimura |
Domain of Applicability, Essentiality of the Key Events, Weight of Evidence Summary, and Background updated. |
| January 06, 2019 20:02 |
Yutaka Kimura |
Relationship:1826 was added to AOP. |
| January 06, 2019 20:02 |
Yutaka Kimura |
Relationship:1825 was added to AOP. |
| January 06, 2019 20:01 |
Yutaka Kimura |
Relationship:1824 was removed from AOP. |
| January 06, 2019 20:00 |
Yutaka Kimura |
Relationship:1824 was added to AOP. |
| January 06, 2019 19:58 |
Yutaka Kimura |
Event:1573 was added to AOP. |
| January 06, 2019 19:57 |
Yutaka Kimura |
Event:983 was removed from AOP. |
| January 06, 2019 19:57 |
Yutaka Kimura |
Event:1569 was removed from AOP. |
| January 06, 2019 19:57 |
Yutaka Kimura |
Event:1568 was removed from AOP. |
| January 06, 2019 19:57 |
Yutaka Kimura |
Event:1567 was removed from AOP. |
| January 06, 2019 19:56 |
Yutaka Kimura |
Event:1566 was removed from AOP. |
| January 06, 2019 19:56 |
Yutaka Kimura |
Event:1565 was removed from AOP. |
| January 06, 2019 19:56 |
Yutaka Kimura |
Relationship:1822 was removed from AOP. |
| January 06, 2019 19:56 |
Yutaka Kimura |
Relationship:1819 was removed from AOP. |
| January 06, 2019 19:56 |
Yutaka Kimura |
Relationship:1815 was removed from AOP. |
| January 06, 2019 19:55 |
Yutaka Kimura |
Relationship:1823 was removed from AOP. |
| January 06, 2019 19:55 |
Yutaka Kimura |
Relationship:1821 was removed from AOP. |
| January 06, 2019 19:55 |
Yutaka Kimura |
Relationship:1820 was removed from AOP. |
| January 06, 2019 19:55 |
Yutaka Kimura |
Relationship:1818 was removed from AOP. |
| January 06, 2019 19:54 |
Yutaka Kimura |
Relationship:1817 was removed from AOP. |
| January 06, 2019 19:54 |
Yutaka Kimura |
Relationship:1816 was removed from AOP. |
| December 25, 2018 04:17 |
Yutaka Kimura |
Authors updated. |
| December 25, 2018 00:14 |
Yutaka Kimura |
Relationship:1823 was added to AOP. |
| December 25, 2018 00:12 |
Yutaka Kimura |
Relationship:1822 was added to AOP. |
| December 25, 2018 00:10 |
Yutaka Kimura |
Relationship:1821 was added to AOP. |
| December 25, 2018 00:09 |
Yutaka Kimura |
Relationship:1820 was added to AOP. |
| December 25, 2018 00:06 |
Yutaka Kimura |
Relationship:1819 was added to AOP. |
| December 25, 2018 00:05 |
Yutaka Kimura |
Relationship:1818 was added to AOP. |
| December 25, 2018 00:03 |
Yutaka Kimura |
Relationship:1817 was added to AOP. |
| December 25, 2018 00:03 |
Yutaka Kimura |
Relationship:1816 was added to AOP. |
| December 25, 2018 00:01 |
Yutaka Kimura |
Relationship:1815 was added to AOP. |
| December 25, 2018 00:01 |
Yutaka Kimura |
Relationship:1814 was added to AOP. |
| December 24, 2018 23:56 |
Yutaka Kimura |
Relationship:1813 was added to AOP. |
| December 24, 2018 23:52 |
Yutaka Kimura |
Event:1572 was added to AOP. |
| December 24, 2018 23:47 |
Yutaka Kimura |
Event:1571 was added to AOP. |
| December 24, 2018 23:44 |
Yutaka Kimura |
Event:1570 was added to AOP. |
| December 24, 2018 23:41 |
Yutaka Kimura |
Event:983 was added to AOP. |
| December 24, 2018 23:26 |
Yutaka Kimura |
Event:986 was added to AOP. |
| December 24, 2018 23:24 |
Yutaka Kimura |
Event:1569 was added to AOP. |
| December 24, 2018 23:22 |
Yutaka Kimura |
Event:1568 was added to AOP. |
| December 24, 2018 23:20 |
Yutaka Kimura |
Event:1567 was added to AOP. |
| December 24, 2018 23:19 |
Yutaka Kimura |
Event:1566 was added to AOP. |
| December 24, 2018 23:17 |
Yutaka Kimura |
Event:1565 was added to AOP. |
| December 20, 2018 20:02 |
Yutaka Kimura |
AOP created. |