API
Created at
Updated at
My DART AOPs
AOP collection · 11 items · Created by Clemens Wittwehr On October 13, 2026
Submitted

A collection of AOPs considered related to Developmental and Reproductive Toxicity

Inflammation-Related Key Events
Event collection · 17 items · Created by Katarina Živančević On August 28, 2026
Draft

Key Events related to different types of inflammation across diverse Adverse Outcome Pathways following exposure to different chemical, physical, or biological stressors.

Adverse Outcome Pathways with Reactive Oxygen Species as a MIE
AOP collection · 31 items · Created by Katarina Živančević On August 28, 2026
Draft

AOPs in which increased reactive oxygen species (ROS) serves as a molecular initiating event (MIE), leading to diverse adverse outcomes following exposure to different chemical, physical, or biolog...

Lung cancer AOPs
AOP collection · 6 items · Created by Katarina Živančević On August 27, 2026
Submitted

AOPs related to lung cancer development or progression caused by chemical, physical, or biological stressors.

Network of Reactive Oxygen Species (ROS)
AOP collection · 15 items · Created by Shihori Tanabe On August 19, 2026
Submitted

AOPs linked with ROS-related KEs discussed at the Mystery of ROS consortium are collected. Ref. 1: Tanabe S, Beaton D, Chauhan V, Choi I, Danielsen PH, Delrue N, Esterhuizen M, Filipovska J, Fitz...

EDSP
AOP collection · 24 items · Created by Dan Villeneuve On August 11, 2026
Draft

A collection of AOPs linking endocrine MIEs or early KEs to endpoints measured in guideline studies relevant to the U.S. Endocrine Disruptor Screening Program.

Immunotoxicity AOPs
AOP collection · 20 items · Created by Alexandra Schaffert On August 10, 2026
Submitted

AOPs related to an adverse alteration of immune system function or integrity caused by a stressor, resulting in impaired immune defense, inappropriate immune activation, hypersensitivity, autoimmun...

Cell death
Event collection · 0 items · Created by Travis Karschnik On July 13, 2026
Draft

testing

AOP Network linking nAChR activation to colony death/failure in social bees
AOP collection · 6 items · Created by Dan Villeneuve On July 5, 2026
Approved

Taxonomic domain of applicability of this network for other Apis and non-Apis bee species was examined by Jensen et al. 2022. https://doi.org/10.1002/etc.5501