AOP-Wiki

Purpose: AOPs related to lung cancer development or progression caused by chemical, physical, or biological stressors.
Creation Strategy: Manual inspection of AOs and AOP titles for: *Lung cancer *Lung carcinoma *Lung neoplasms *Small cell lung cancer *Non-small cell lung cancer *Pulmonary tumorigenesis *Lung tumor development *Lung cancer progression *Malignant transformation of lung cells

ID	Title	License	OECD Status
272	Deposition of energy leading to lung cancer	BY-SA	WPHA/WNT Endorsed
303	Frustrated phagocytosis-induced lung cancer	BY-SA	Under Development
416	Aryl hydrocarbon receptor activation leading to lung cancer through IL-6 toxicity pathway	BY-SA
417	Aryl hydrocarbon receptor activation leading to lung cancer through AHR-ARNT toxicity pathway	BY-SA
420	Aryl hydrocarbon receptor activation leading to lung cancer through sustained NRF2 toxicity pathway	BY-SA
451	Interaction with lung resident cell membrane components leads to lung cancer	BY-SA

Lung cancer AOPs