AOP-Wiki

API

All Key Events

Showing 1926 to 1944 of 1944 Key Events

ID	Title	Event Component Count	Biological Organization	Created At	Last Updated	AOPs

2433	Decrease, Telomere attrition Short Name Telomere attrition	0	Molecular	Jul 9, 2026	Jul 9, 2026	None
2434	Disruption, Mitochondrial dysfunction Short Name Mitochondrial dysfunction	0	Cellular	Jul 9, 2026	Jul 9, 2026	None
2435	Increase, Myocardial and vascular structural remodeling Short Name	0	Tissue	Jul 9, 2026	Jul 9, 2026	645: Binding and activation of AhR lead to cardiovascular aging
2436	Increase, Systemic inflammation Short Name Systemic inflammation	0	Cellular	Jul 9, 2026	Jul 9, 2026	None
2437	Increase, Blood pressure elevation Short Name Blood pressure elevation	0	Tissue	Jul 9, 2026	Jul 9, 2026	None
2438	Increase, Cardiovascular aging Short Name Cardiovascular aging	0	Individual	Jul 9, 2026	Jul 9, 2026	645: Binding and activation of AhR lead to cardiovascular aging
2439	Increase, Telomere attrition Short Name Increase, Telomere attrition	0	Molecular	Jul 9, 2026	Jul 9, 2026	645: Binding and activation of AhR lead to cardiovascular aging
2440	Increase, Hepatic inflammation Short Name Hepatic inflammation	0	Tissue	Jul 9, 2026	Jul 9, 2026	None
2441	Increased , Fatty acid synthesis and transport Short Name	0	Tissue	Jul 9, 2026	Jul 9, 2026	646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
2442	Increase, Abnormal lipid accumulation Short Name Abnormal lipid accumulation	0	Organ	Jul 9, 2026	Jul 9, 2026	None
2443	Increase, Hepatocyte injury Short Name Hepatocyte injury	0	Tissue	Jul 9, 2026	Jul 9, 2026	None
2444	Increase, Progesterone resistance Short Name Progesterone resistance	0	Cellular	Jul 17, 2026	Jul 17, 2026	577: AhR activation leading to endometriosis
2445	Increase, Blood pressure Short Name Blood pressure	0	Organ	Jul 24, 2026	Jul 24, 2026	645: Binding and activation of AhR lead to cardiovascular aging
2446	Increase, lipid accumulation Short Name lipid accumulation	0	Tissue	Jul 24, 2026	Jul 24, 2026	646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
2447	Increase, Keap1 cysteine modification Short Name Keap1 cysteine modification	0	Molecular	Aug 12, 2026	Aug 12, 2026	None
2448	Brain insulin-degrading enzyme (IDE), inhibition Short Name IDE inhibition	0	Molecular	Aug 31, 2026	Aug 31, 2026	652: Inhibition of brain insulin-degrading enzyme (IDE) leads to cognitive decline (adult)
2449	Brain amyloid-beta (Aβ) accumulation, increased Short Name Abeta accumulation	0	Cellular	Aug 31, 2026	Aug 31, 2026	652: Inhibition of brain insulin-degrading enzyme (IDE) leads to cognitive decline (adult)
2450	Cognitive Decline (Adult) Short Name Cognitive Decline (Adult)	0	Individual	Aug 31, 2026	Aug 31, 2026	652: Inhibition of brain insulin-degrading enzyme (IDE) leads to cognitive decline (adult)
2451	Increase, TDP-43 aggregation Short Name TDP-43 aggregation	0	Cellular	Sep 6, 2026	Sep 6, 2026	636: Increase in reactive oxygen species (ROS) leading to human amyotrophic lateral sclerosis (ALS)