| 344 |
373: Formation, Pro-mutagenic DNA Adducts |
377: Increased, Proliferation/Clonal Expansion of Mutant Cells (Pre-Neoplastic Lesions/Altered H |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 345 |
373: Formation, Pro-mutagenic DNA Adducts |
378: Tumorigenesis, Hepatocellular carcinoma |
Nov 29, 2016 |
Nov 29, 2016 |
1 AOP
|
| 352 |
373: Formation, Pro-mutagenic DNA Adducts |
384: Increased, Clonal Expansion / Cell Proliferatin to form Pre-Neoplastic Altered Hepatic Foci |
Nov 29, 2016 |
Nov 29, 2016 |
None
|
| 548 |
373: Formation, Pro-mutagenic DNA Adducts |
493: Increased, Insufficient repair or mis-repair of pro-mutagenic DNA adducts |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 551 |
373: Formation, Pro-mutagenic DNA Adducts |
491: Clonal Expansion/Cell Proliferation, to form Altered Hepatic Foci (AHF) |
Nov 29, 2016 |
Nov 29, 2016 |
1 AOP
|
| 3762 |
373: Formation, Pro-mutagenic DNA Adducts |
1194: Increase, DNA Damage |
Mar 29, 2026 |
Mar 29, 2026 |
1 AOP
|
| 1062 |
976: Formation, The binding of FK506 with FKBP12 |
980: Inhibition, Calcineurin Activity |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 2437 |
1903: foxi1 expression, increased |
1904: six1b expression, increased |
Jul 14, 2021 |
Oct 28, 2021 |
1 AOP
|
| 2447 |
1911: FOXJ1 Protein, Decreased |
1912: Motile Cilia Number/Length, Decreased |
Jul 23, 2021 |
Aug 2, 2021 |
1 AOP
|
| 1925 |
1646: Frizzled activation |
1647: GSK3beta inactivation |
May 29, 2019 |
May 29, 2019 |
None
|
| 1962 |
1668: Frustrated phagocytosis |
87: Release, Cytokine |
Jul 3, 2019 |
Aug 13, 2019 |
1 AOP
|
| 2415 |
1668: Frustrated phagocytosis |
1496: Increased proinflammatory mediators |
Jul 6, 2021 |
Jul 6, 2021 |
1 AOP
|
| 2416 |
1668: Frustrated phagocytosis |
1115: Increase, ROS |
Jul 6, 2021 |
Jul 6, 2021 |
1 AOP
|
| 1733 |
1513: General Apoptosis |
1514: Neurodegeneration |
Apr 4, 2018 |
Apr 5, 2018 |
1 AOP
|
| 2977 |
1513: General Apoptosis |
885: Increase, Cancer |
Jul 31, 2023 |
Oct 19, 2023 |
2 AOPs
|
| 1289 |
1236: Generation of novel epitopes , Antigen presentation |
1237: Sensitization, Immune system |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 684 |
682: Generation, Amplified excitatory postsynaptic potential (EPSP) |
616: Occurrence, A paroxysmal depolarizing shift |
Nov 29, 2016 |
May 15, 2018 |
1 AOP
|
| 2418 |
1896: Genomic instability |
870: Increase, Cell Proliferation |
Jul 6, 2021 |
Jul 6, 2021 |
1 AOP
|
| 2973 |
1896: Genomic instability |
2154: endometrioid adenocarcinoma Type I |
Jul 27, 2023 |
Mar 27, 2025 |
1 AOP
|
| 1645 |
494: GR Agonist, Activation |
496: Decreased Leydig Cells |
Aug 11, 2017 |
Aug 11, 2017 |
1 AOP
|
| 1646 |
494: GR Agonist, Activation |
495: Repressed expression of steroidogenic enzymes |
Aug 11, 2017 |
Aug 11, 2017 |
1 AOP
|
| 1686 |
1488: Glutamate dyshomeostasis |
55: Cell injury/death |
Nov 9, 2017 |
Feb 6, 2020 |
1 AOP
|
| 1691 |
1488: Glutamate dyshomeostasis |
386: Neuronal network function, Decreased |
Nov 9, 2017 |
Nov 9, 2017 |
None
|
| 1378 |
1290: Glutathione homeostasis |
1291: Hepatotoxicity |
Feb 15, 2017 |
Feb 15, 2017 |
1 AOP
|
| 1374 |
1287: Glutathione synthesis |
1288: Activation, 3-hydroxy-3-methylglutaryl-CoA reductase gene |
Feb 15, 2017 |
Feb 15, 2017 |
1 AOP
|