AOPs

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Showing 276 to 300 of 581 AOPs

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ID Title Point of Contact License MIE AO OECD Status OECD Project
363 Thyroperoxidase inhibition leading to altered visual function via altered retinal layer structure Lucia Vergauwen BY-SA 279: Thyroperoxidase, Inhibition Under Review 1.35
362 Immune mediated hepatitis Jung-Hwa Oh BY-SA 1814: benzoquinone imine and acylglucuronide metabolites 1820: Immune mediated hepatitis
361 Sulfonylureareceptor binding leading to mortality Simon Schmid BY-SA 1525: Increase, Sulfonylurea receptor binding 350: Increase, Mortality Under Development 1.94
360 Chitin synthase 1 inhibition leading to mortality Simon Schmid BY-SA 1522: Inhibition, Chitin synthase 1 350: Increase, Mortality WPHA/WNT Endorsed 1.94
359 Chitobiase inhibition leading to mortality Simon Schmid BY-SA 1807: Inhibition, Chitobiase 350: Increase, Mortality Under Development 1.94
358 Chitinase inhibition leading to mortality Simon Schmid BY-SA 1806: Inhibition, Chitinase 350: Increase, Mortality Under Development 1.94
349 Inhibition of 11β-hydroxylase leading to decresed population trajectory Young Jun Kim BY-SA 1796: 11β-hydroxylase inhibition 360: Decrease, Population growth rate Under Development 1.93
348 Inhibition of 11β-Hydroxysteroid Dehydrogenase leading to decreased population trajectory Young Jun Kim BY-SA 1799: Inhibition of 11β-HSD 360: Decrease, Population growth rate Under Development 1.93
347 Toll-like receptor 4 activation and peroxisome proliferator-activated receptor gamma inactivation leading to pulmonary fibrosis Seokjoo Yoon BY-SA 1458: Pulmonary fibrosis
346 Aromatase inhibition leads to male-biased sex ratio via impacts on gonad differentiation Kelvin Santana Rodriguez BY-SA 36: Inhibition, Aromatase 360: Decrease, Population growth rate WPHA/WNT Endorsed 1.12
345 Androgen receptor (AR) antagonism leading to decreased fertility in females Terje Svingen BY-SA 26: Antagonism, Androgen receptor Under Development 1.109
344 Androgen receptor (AR) antagonism leading to nipple retention (NR) in male (mammalian) offspring Terje Svingen BY-SA 26: Antagonism, Androgen receptor 1786: Nipple retention (NR), increased Under Development 1.108
343 Ecdysone receptor antagonism leading to mortality via mis-timed ecdysone receptor-responsive nuclear receptor cascade You Song BY-SA 2374: Increase, Ecdysone receptor antagonism
342 Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade You Song BY-SA 103: Increase, Ecdysone receptor hyperactivation
341 DNA methyltransferase inhibition leading to transgenerational effects (2) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
340 DNA methyltransferase inhibition leading to transgenerational effects (1) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
339 DNA methyltransferase inhibition leading to population decline (4) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
338 DNA methyltransferase inhibition leading to population decline (3) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
337 DNA methyltransferase inhibition leading to population decline (2) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
336 DNA methyltransferase inhibition leading to population decline (1) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
335 AOP for urothelial carcinogenesis due to chemical cytotoxicity by mitochondrial impairment Nathalia Pereira Souza BY-SA 177: Increase, Mitochondrial dysfunction 1763: Urothelial Tumor
334 Glucocorticoid Receptor Agonism Leading to Impaired Fin Regeneration Alexander Cole BY-SA 122: Increase, Glucocorticoid receptor activation 360: Decrease, Population growth rate
333 Reactive oxygen species leading to growth inhibition via protein oxidation and cell death You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
332 Reactive oxygen species leading to growth inhibition via protein oxidation and decreased cell proliferation You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
331 Reactive oxygen species leading to growth inhibition via lipid peroxidation and cell death You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth