Key Event Relationships (KERs)

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Showing 2826 to 2850 of 3102 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
562 561: Reduced, Food storage 566: impaired, Larval development Nov 29, 2016 Dec 3, 2016
1557 1419: Reduced, FXR activity 1420: Reduced, SHP activity Jun 2, 2017 Jun 2, 2017
1553 1415: Reduced, GABA-A receptor activation 1416: Decreased, intracellular chloride Jun 2, 2017 Jun 2, 2017
691 689: Reduced, Gonadotropin releasing hormone, hypothalamus 690: Reduced, Luteinizing hormone (LH), plasma Nov 29, 2016 Dec 3, 2016
2231 1008: Reduced, Hearing 351: Increased Mortality Dec 8, 2020 Dec 8, 2020
1561 1423: Reduced, HSD17B4 activity 1424: Reduced, fatty acid beta oxidation Jun 2, 2017 Jun 2, 2017
692 690: Reduced, Luteinizing hormone (LH), plasma 691: Reduced, Maturation inducing steroid, plasma Nov 29, 2016 Dec 3, 2016
694 692: Reduced, Maturation inducing steroid receptor signalling, oocyte 693: Increased, cyclic adenosine monophosphate Nov 29, 2016 Dec 3, 2016
698 692: Reduced, Maturation inducing steroid receptor signalling, oocyte 695: Upregulated, Spindle assembly checkpoint protein Mad2-oocyte Nov 29, 2016 Dec 3, 2016
693 691: Reduced, Maturation inducing steroid, plasma 692: Reduced, Maturation inducing steroid receptor signalling, oocyte Nov 29, 2016 Dec 3, 2016
697 694: Reduced, Meiotic prophase I/metaphase I transition, oocyte 675: Reduced, Reproductive Success Nov 29, 2016 Dec 3, 2016
1536 1405: Reduced, mucosal defense 1385: Activated, gastric ulcer formation Jun 2, 2017 Jun 2, 2017
1548 1405: Reduced, mucosal defense 1412: Helicobacter pylori infection Jun 2, 2017 Jun 2, 2017 None
679 678: Reduced, Pheromone release 674: Reduced, Ability to attract spawning mates Nov 29, 2016 Dec 3, 2016
1533 1403: Reduced, platelet aggregation 1385: Activated, gastric ulcer formation Jun 2, 2017 Jun 2, 2017
1028 1004: Reduced, Posterior swim bladder inflation 1005: Reduced, Swimming performance Nov 29, 2016 Sep 3, 2021
1031 1004: Reduced, Posterior swim bladder inflation 1007: Reduced, Anterior swim bladder inflation Nov 29, 2016 Nov 20, 2020 None
2213 1004: Reduced, Posterior swim bladder inflation 351: Increased Mortality Nov 30, 2020 Sep 8, 2021
1560 1422: Reduced, PPARalpha 1423: Reduced, HSD17B4 activity Jun 2, 2017 Jun 2, 2017
1551 1413: Reduced, presynaptic neuron 2 activity 1414: Decreased, GABA Jun 2, 2017 Jun 2, 2017
357 383: Reduced, Presynaptic release of glutamate 385: Synaptogenesis, Decreased Nov 29, 2016 Nov 29, 2016
690 687: Reduced, Prostaglandin E2 concentration, hypothalamus 689: Reduced, Gonadotropin releasing hormone, hypothalamus Nov 29, 2016 Dec 3, 2016
672 671: Reduced, Prostaglandin F2alpha concentration, plasma 673: Reduced, Spawning behavior Nov 29, 2016 Dec 3, 2016
678 671: Reduced, Prostaglandin F2alpha concentration, plasma 678: Reduced, Pheromone release Nov 29, 2016 Dec 3, 2016
671 672: Reduced, Prostaglandin F2alpha synthesis, ovary 671: Reduced, Prostaglandin F2alpha concentration, plasma Nov 29, 2016 Dec 3, 2016