| 2378 |
Impaired axonal insulation
Short Name
Impaired axonal insulation
|
0 |
Tissue |
Oct 8, 2025 |
Oct 8, 2025 |
610: Decreased thyroid hormone levels in the brain regulated via transport, metabolism and TR activation leading to decreased cognition and motor function
|
| 2377 |
Decrease, neural network maturation
Short Name
neural network formation
|
0 |
Tissue |
Oct 8, 2025 |
Oct 8, 2025 |
610: Decreased thyroid hormone levels in the brain regulated via transport, metabolism and TR activation leading to decreased cognition and motor function
|
| 2376 |
Inhibition, organic anion-transporting polypeptide 1C1 (OATP1C1)
Short Name
Inhibition, OATP1C1
|
0 |
Molecular |
Oct 8, 2025 |
Oct 8, 2025 |
610: Decreased thyroid hormone levels in the brain regulated via transport, metabolism and TR activation leading to decreased cognition and motor function
|
| 2375 |
Decrease, Mis-timed ecdysone receptor-responsive nuclear receptor cascade
Short Name
Decrease, Mis-timed EcR-responsive NR cascade
|
0 |
Cellular |
Sep 29, 2025 |
Sep 29, 2025 |
2 AOPs
|
| 2374 |
Increase, Ecdysone receptor antagonism
Short Name
Increase, EcR antagonism
|
0 |
Molecular |
Sep 29, 2025 |
Sep 29, 2025 |
2 AOPs
|
| 2373 |
Increase, Mis-timed ecdysone receptor-responsive nuclear receptor cascade
Short Name
Increase, Mis-timed EcR-responsive NR cascade
|
0 |
Cellular |
Sep 29, 2025 |
Sep 29, 2025 |
342: Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade
|
| 2372 |
Squamous metaplasia, Increase
Short Name
Squamous metaplasia, Increase
|
1 |
Cellular |
Sep 12, 2025 |
Sep 16, 2025 |
None
|
| 2371 |
Increased cortisol
Short Name
Increased cortisol
|
2 |
Cellular |
Sep 11, 2025 |
Oct 31, 2025 |
604: Binding of Alpha 1-Adrenergics to Antagonists Leading to Depression
|
| 2370 |
Antagonism binding, α1-Adrenoreceptor
Short Name
A1AR Antagonism
|
1 |
Cellular |
Sep 11, 2025 |
Oct 7, 2025 |
604: Binding of Alpha 1-Adrenergics to Antagonists Leading to Depression
|
| 2369 |
Granulosa cell damage
Short Name
Granulosa cell damage
|
0 |
Cellular |
Sep 9, 2025 |
Sep 9, 2025 |
595: Emerging OPFRS reproductive outcome pathway
|
| 2368 |
immature oocyte
Short Name
immature oocyte
|
0 |
Cellular |
Sep 9, 2025 |
Sep 9, 2025 |
None
|
| 2367 |
Steroidogenesis Dysregulation
Short Name
Steroidogenesis Dysregulation
|
0 |
Cellular |
Sep 9, 2025 |
Sep 9, 2025 |
595: Emerging OPFRS reproductive outcome pathway
|
| 2366 |
ovarian retardation
Short Name
ovarian retardation
|
0 |
Organ |
Sep 9, 2025 |
Sep 9, 2025 |
595: Emerging OPFRS reproductive outcome pathway
|
| 2365 |
Anogenital distance (AGD), increased
Short Name
AGD, increased
|
0 |
Tissue |
Sep 5, 2025 |
Dec 8, 2025 |
547: Androgen receptor agonism leading to long anogenital distance in female offspring
|
| 2363 |
Elevated mitochondrial ROS and dysfunction
Short Name
Mito ROS dysfunction
|
1 |
Cellular |
Sep 5, 2025 |
Oct 3, 2025 |
2 AOPs
|
| 2362 |
Redox cycling of a chemical by mitochondria
Short Name
Redox cycling
|
0 |
Molecular |
Sep 5, 2025 |
Oct 3, 2025 |
593: Redox cycling of a chemical by mitochondria leads to degeneration of nigrostriatal dopaminergic neurons
|
| 2361 |
Hypothalamus–Pituitary–Gonad) axis disruption
Short Name
HPG axis disruption
|
0 |
Organ |
Sep 2, 2025 |
Sep 2, 2025 |
None
|
| 2360 |
Activation of steroidogenesis
Short Name
steroidogenesis
|
0 |
Cellular |
Sep 2, 2025 |
Sep 2, 2025 |
None
|
| 2359 |
HPG axis
Short Name
HPG axis
|
0 |
Molecular |
Aug 29, 2025 |
Aug 29, 2025 |
None
|
| 2358 |
endocrine disruption
Short Name
endocrine disruption
|
0 |
Molecular |
Aug 29, 2025 |
Aug 29, 2025 |
None
|
| 2357 |
ovary
Short Name
ovary retardation
|
0 |
Molecular |
Aug 29, 2025 |
Aug 29, 2025 |
None
|
| 2356 |
vitellogenin
Short Name
vtg
|
0 |
Molecular |
Aug 29, 2025 |
Aug 29, 2025 |
None
|
| 2355 |
Disrupted, Spermatogenesis and Sperm quality
Short Name
Disrupted, Spermatogenesis and Sperm quality
|
0 |
Organ |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|
| 2354 |
Activation, Apoptosis signaling
Short Name
Activation, Apoptosis signaling
|
0 |
Cellular |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|
| 2353 |
Disrupted, energy metabolism
Short Name
Disrupted, energy metabolism
|
0 |
Cellular |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|