| 2352 |
Increased, MMP
Short Name
Increased, MMP
|
0 |
Cellular |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|
| 2351 |
Increased, OXPHOS
Short Name
Increased, OXPHOS
|
0 |
Cellular |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|
| 2350 |
Decreased, Glycolysis
Short Name
Decreased, Glycolysis
|
0 |
Cellular |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|
| 2349 |
Inhibition of LDH activity
Short Name
Inhibition of LDH activity
|
0 |
Molecular |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|
| 2348 |
Inhibition, Liver regeneration
Short Name
Inhibition, Liver regeneration
|
0 |
Organ |
Aug 16, 2025 |
Aug 16, 2025 |
591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
|
| 2347 |
Increase, Lipid degradation
Short Name
Increase, Lipid degradation
|
0 |
Cellular |
Aug 16, 2025 |
Aug 16, 2025 |
591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
|
| 2346 |
Decrease, Proliferating Cell Nuclear Antigen
Short Name
Downregulation, PCNA
|
0 |
Molecular |
Aug 16, 2025 |
Aug 16, 2025 |
591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
|
| 2345 |
Activation, MAPK
Short Name
Activation, MAPK
|
0 |
Molecular |
Aug 16, 2025 |
Aug 16, 2025 |
591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
|
| 2344 |
Upregulation, growth arrest and DNA-damage-inducible beta a
Short Name
Upregulation, gadd45ba
|
0 |
Molecular |
Aug 16, 2025 |
Aug 16, 2025 |
591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
|
| 2343 |
Cuproptosis, increased
Short Name
Cuproptosis, increased
|
0 |
Cellular |
Aug 13, 2025 |
Oct 16, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2342 |
Iron-sulfur cluster assembly, impaired
Short Name
Fe-S cluster assembly, impaired
|
0 |
Molecular |
Aug 13, 2025 |
Oct 30, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2341 |
Tricarboxylic acid (TCA) cycle, disrupted
Short Name
TCA cycle, disrupted
|
0 |
Molecular |
Aug 13, 2025 |
Oct 16, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2340 |
Oligomerisation of dihydrolipoamide acetyltransferase (DLAT), increased
Short Name
Oligomerisation of DLAT, increased
|
0 |
Molecular |
Aug 13, 2025 |
Oct 16, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2339 |
Intracellular copper, increased
Short Name
Intracellular copper, increased
|
0 |
Cellular |
Aug 13, 2025 |
Oct 16, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2337 |
Increase, perilipin-2
Short Name
Increase, PLIN2
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2336 |
Increase, SREBF1
Short Name
Increase, SREBF1
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2335 |
Increase, body mass index
Short Name
Increase, BMI
|
0 |
Individual |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2334 |
Increase, DGAT1
Short Name
Increase, DGAT1
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2333 |
Increase, Fat mass
Short Name
Increase, Fat mass
|
0 |
Organ |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2332 |
Increase, Lipid droplet
Short Name
Increase, Lipid droplet
|
0 |
Cellular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2331 |
Activation, Mineralocorticoid Receptor
Short Name
Activation, MR
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2330 |
Sine oculis homeobox 1 protein expression, increased
Short Name
SIX1 protein expression, increased
|
1 |
Molecular |
Jul 8, 2025 |
Dec 17, 2025 |
167: Early-life estrogen receptor agonism leading to endometrial adenosquamous carcinoma via promotion of sine oculis homeobox 1 progenitor cells
|
| 2329 |
Sine oculis homeobox 1 gene expression, increased
Short Name
SIX1 gene expression, increased
|
1 |
Molecular |
Jul 8, 2025 |
Sep 11, 2025 |
167: Early-life estrogen receptor agonism leading to endometrial adenosquamous carcinoma via promotion of sine oculis homeobox 1 progenitor cells
|
| 2327 |
Decrease, Cell growth
Short Name
Decrease, Cell growth
|
0 |
Cellular |
May 23, 2025 |
May 23, 2025 |
3 AOPs
|
| 2326 |
CTL cytotoxic activity disruption
Short Name
CTL cytotoxicity
|
0 |
Cellular |
May 22, 2025 |
Feb 24, 2026 |
578: AhR activation leading to cancer progression via immunosuppression
|