Key Event Relationships (KERs)

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Showing 1701 to 1725 of 3102 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
1978 185: Increase, Mutations 870: Increase, Cell Proliferation Aug 29, 2019 Mar 8, 2024
1984 185: Increase, Mutations 1556: Increase, lung cancer Aug 29, 2019 Jan 10, 2023
2609 185: Increase, Mutations 1980: Increase,miRNA levels Mar 22, 2022 Aug 27, 2023
894 876: Increase, Mutations in Critical Genes 872: Increase, Site of Contact Nasal Tumors Nov 29, 2016 Dec 1, 2016
1356 1272: Increase, Myofibroblast expansion 1274: Production of α-smooth muscle actin Feb 15, 2017 Feb 15, 2017 None
1443 1341: Increase, myosin light chain phosphorylation 1342: Increase, vascular smooth muscle contraction Apr 14, 2017 Apr 14, 2017
1874 1607: Increase, Necrosis 350: Increase, Mortality Mar 19, 2019 Mar 19, 2019 None
2122 1607: Increase, Necrosis 1777: Increase, Ovarian follicle breakdown May 8, 2020 May 8, 2020 None
2177 1607: Increase, Necrosis 1809: Increase, Tissue/organ damage Nov 2, 2020 Nov 2, 2020 None
2465 1607: Increase, Necrosis 759: Increased, Kidney Failure Aug 11, 2021 Aug 11, 2021
726 733: Increase, Necrosis (terminal bronchiolar cells) 734: Increase, Regenerative cell proliferation (terminal bronchiolar epithelial cells) Nov 29, 2016 Dec 3, 2016
1344 1264: Increase, E75b expression 1265: Decrease, Ftz-f1 expression Feb 9, 2017 Feb 9, 2017
2104 1775: Increase, Oocyte apoptosis 1366: Decrease, Oogenesis Apr 30, 2020 Apr 30, 2020
2386 1775: Increase, Oocyte apoptosis 406: decreased, Fertility May 12, 2021 May 12, 2021
2400 1775: Increase, Oocyte apoptosis 1696: Decrease of egg production and cummulative fecundity May 18, 2021 May 18, 2021
2113 1780: Increase, Oocyte apoptosis (F3) 1782: Decrease, Oogenesis (F3) Apr 30, 2020 Apr 30, 2020
1747 1526: Increase, Opening of voltage-dependent calcium channel 1523: Decrease, Cuticular chitin content May 24, 2018 May 24, 2018
2107 1777: Increase, Ovarian follicle breakdown 1366: Decrease, Oogenesis Apr 30, 2020 Apr 30, 2020
2560 1777: Increase, Ovarian follicle breakdown 328: Decrease, Fecundity Feb 4, 2022 Feb 4, 2022 None
2118 1784: Increase, Ovarian follicle breakdown (F3) 1782: Decrease, Oogenesis (F3) Apr 30, 2020 Apr 30, 2020
2106 1776: Increase, Ovarian somatic cell apoptosis 1777: Increase, Ovarian follicle breakdown Apr 30, 2020 Apr 30, 2020
2117 1783: Increase, Ovarian somatic cell apoptosis (F3) 1784: Increase, Ovarian follicle breakdown (F3) Apr 30, 2020 Apr 30, 2020
1909 1634: Increase, Oxidative DNA damage 155: Inadequate DNA repair May 19, 2019 Mar 8, 2024
1913 1634: Increase, Oxidative DNA damage 1635: Increase, DNA strand breaks May 19, 2019 Dec 17, 2024
1914 1634: Increase, Oxidative DNA damage 185: Increase, Mutations May 19, 2019 Jan 9, 2023